At Laser & Cosmetic Surgery Specialists in Newburgh, NY, Dr. Ran Rubinstein and his team provide PDGF-BB injections to help patients improve hair density and scalp health without the need for surgery, blood draws, or microneedling. This innovative treatment uses growth factors to stimulate the body’s natural ability to regenerate healthy hair follicles, offering results that are more predictable and potent than older methods.
What Is PDGF-BB?
PDGF-BB stands for platelet-derived growth factor-BB, a protein that plays a crucial role in tissue healing and cell regeneration. While platelet-rich plasma (PRP) also contains growth factors, PDGF-BB is isolated and concentrated to provide up to 300,000 times the potency of PRP. This makes it a powerful option for patients seeking hair restoration treatments that deliver consistent and noticeable results.
Unlike PRP, which requires drawing the patient’s blood and processing it before reinjection, PDGF-BB is provided in a ready-to-use form. This means treatments are shorter, less invasive, and more comfortable for patients.
How PDGF-BB Stimulates Hair Growth
Hair thinning often occurs when follicles shrink or enter extended resting phases. PDGF-BB works by stimulating dormant hair follicles, encouraging them to re-enter the growth cycle. The treatment also improves blood supply in the scalp by promoting new blood vessel formation, which supports healthier, more resilient hair over time.
By creating a more nourishing environment in the scalp, PDGF-BB not only helps stimulate new growth but also strengthens existing hair. Over the course of several treatments, many patients notice increased thickness, improved texture, and a fuller appearance.


Treatment Process
PDGF-BB hair treatment is performed in-office and takes only about 10 minutes once you are prepared. Here’s what patients can expect:
- Aesthetic injectors (PA or NP) administer the treatment.
- Injections are placed across the areas of the scalp showing thinning or loss.
- No anesthesia is required, though patients may feel mild pressure during treatment.
- Because no blood draw or microneedling is needed, the process is simple and highly tolerable.
This streamlined approach makes PDGF-BB an attractive option for patients who want effective hair restoration without the inconvenience of more invasive procedures.
Schedule a Consultation
If you are ready to explore a more advanced approach to hair restoration, schedule a consultation at Laser & Cosmetic Surgery Specialists in Newburgh, NY. Dr. Rubinstein and his team will evaluate your concerns and create a personalized plan that may include PDGF-BB injections for healthier, fuller hair. Call today to learn more about how this innovative treatment can help you regain confidence.

Recovery and Aftercare
One of the advantages of PDGF-BB injections is the lack of downtime. Patients can resume normal activities right away, but should avoid high-intensity exercise until the following morning.
Some patients may experience temporary tenderness or mild soreness in the treated areas for a few days. Small bumps at injection sites are rare and, if they occur, usually resolve within a few weeks. These side effects are minimal compared to more invasive procedures, and most patients find the treatment very easy to tolerate.
Treatment Timeline and Results
PDGF-BB hair restoration is performed as a series of treatments for the best results:
Initial series
3 sessions spaced about 8 weeks apart
Maintenance
1 session every 6 months to sustain improvements
Because PDGF-BB stimulates natural follicle activity, results develop gradually over time. In the first few weeks, many patients notice subtle changes such as less shedding and existing hairs that appear thicker and healthier. By the third or fourth month, new growth often begins to appear, though it may initially be fine or lighter in color. With continued treatments and regular maintenance, these new hairs thicken and blend with existing strands. Most patients see their most noticeable improvements between six and twelve months after starting treatment, experiencing fuller, thicker hair and improved scalp health. Since PDGF-BB works with the body’s natural hair cycles, improvements continue to build gradually and maintain a natural look.

Risks and Considerations
Like all medical treatments, PDGF-BB injections carry the possibility of side effects, though they are uncommon and usually mild if they occur. These may include temporary soreness at the injection sites for a few days or, more rarely, small bumps under the skin that resolve within 4 weeks. Some patients may also notice minimal visible changes to the scalp right after treatment, but these typically fade quickly.
It is also important to note that while PDGF-BB is FDA-approved for certain medical applications, its use in hair restoration is considered off-label. Off-label treatments are very common in aesthetic medicine, and PDGF-BB is widely performed because of its strong safety profile and proven effectiveness. During your consultation, Dr. Rubinstein and his team will review your health history, treatment goals, and any questions you may have to ensure this option is both safe and appropriate for you.
PDGF-BB vs PRP Hair Restoration
PRP hair restoration has been a popular option for years, but it comes with some limitations. PDGF-BB addresses these issues while delivering superior results.
Potency
PDGF-BB is far more concentrated, providing up to 300,000 times the regenerative power of PRP.
Consistency
PRP relies on the patient’s own blood, and results can vary based on individual factors such as platelet count or overall health. PDGF-BB is standardized, ensuring more reliable outcomes.
Comfort
PRP requires both a blood draw and often microneedling, which can cause discomfort. PDGF-BB does not require either, making the procedure much simpler.
Downtime
Both treatments have minimal downtime, but PDGF-BB patients often experience fewer side effects.
For these reasons, Laser & Cosmetic Surgery Specialists are transitioning most patients from PRP to PDGF-BB. PRP remains available but is no longer the first-line option due to its variability.
Who Is a Candidate?
Ideal candidates for PDGF-BB hair treatment include:
- Men and women noticing thinning hair or reduced density
- Patients who want a nonsurgical, low-discomfort treatment
- Individuals who have tried PRP but want a more effective alternative
- Those seeking natural, gradual improvements in hair growth and scalp health
Patients with advanced baldness may require additional treatment approaches, and a consultation with Dr. Rubinstein and his team will help determine the best plan.


Why Choose Laser & Cosmetic Surgery Specialists?
Patients throughout the Hudson Valley trust Laser & Cosmetic Surgery Specialists for their hair restoration treatments because of the practice’s commitment to advanced regenerative options and personalized care. Dr. Ran Rubinstein, a double board-certified facial plastic surgeon, leads a team of highly trained aesthetic injectors who specialize in nonsurgical treatments that improve patient confidence.
With state-of-the-art technology, a comfortable office setting, and a reputation for natural results, the Newburgh team ensures each patient receives safe, effective, and customized care.