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Biostimulants in Newburgh, NY

Biostimulant injectables, also referred to as regenerative injectables, are an advanced treatment option designed to support natural skin and tissue rejuvenation by encouraging the body to produce its own collagen and elastin. Unlike traditional fillers that simply add volume, biostimulants work gradually to improve skin quality and structure over time. This makes them an excellent choice for patients seeking longer-lasting, more natural results that continue to improve for months after treatment.

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At Laser & Cosmetic Surgery Specialists in Newburgh, NY, patients can benefit from three leading types of biostimulant injectables: PDGF-BB, Sculptra, and Hyperdilute Radiesse. Each works in a unique way but shares the goal of restoring skin health and vitality by using the body’s own regenerative capabilities. Read on to learn more about the different treatment options available, their benefits, what to expect during and after the procedure, and why patients throughout the Hudson Valley choose Dr. Rubinstein and his team for their aesthetic care.

What Are Biostimulants?

Biostimulants, sometimes called regenerative injectables, are injectable treatments that stimulate the body’s natural production of collagen and elastin. These two proteins are critical for healthy, youthful-looking skin. Collagen provides structure and firmness, while elastin maintains flexibility and resilience. As we age, collagen and elastin levels decline, leading to skin laxity, fine lines, and a crepey texture. Biostimulant injections work beneath the skin’s surface to trigger the body to rebuild these essential proteins, gradually improving skin thickness, smoothness, and overall appearance.

Because biostimulants enhance natural regeneration, the results are not immediate but become visible over several weeks to months. Improvements may include tighter skin, better texture, reduction in crepiness, and a refreshed glow. These treatments can also restore lost volume, though more subtly than traditional fillers.

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Types of Biostimulants Available

At Laser & Cosmetic Surgery Specialists, three biostimulant options are offered: PDGF-BB, Sculptra, and Hyperdilute Radiesse. Each is carefully chosen based on the area being treated, the specific concern, and the desired results.

PDGF-BB Injections

PDGF-BB, also known as Platelet-Derived Growth Factor-BB, is an injectable regenerative treatment that stimulates collagen growth and supports new blood vessel formation. This powerful growth factor helps restore skin health from the inside out.

Treatment areas

Can be used on the face, neck, and body to improve tone and texture.

Benefits

Enhances collagen and elastin production, reduces skin crepiness, and promotes a healthy glow.

Treatment course

Typically requires 1–3 sessions depending on the individual. Maintenance is usually a single treatment once a year.

Recovery

Mild swelling or pinkness may occur for a few days to weeks. Some patients may notice small bumps at injection sites that resolve within 4 weeks.

Key advantage

Unlike platelet-rich plasma (PRP), PDGF-BB does not require a blood draw. It is up to 300,000 times more potent than PRP, making it an excellent option for patients seeking effective regenerative treatment with minimal discomfort.

Woman with glowing skin smiling outdoors after PDGF-BB treatment for collagen boost and skin rejuvenation — PDGF-BB stimulates collagen production and supports blood vessel growth for skin regeneration.

Sculptra

Sculptra is an FDA-approved biostimulant made from poly-L-lactic acid (PLLA). It works gradually to stimulate collagen growth, restore facial volume, and improve skin quality.

Treatment areas

Most commonly used on the face to address volume loss in the cheeks, undereyes, temples, and jawline.

Benefits

Improves facial contours, smooths wrinkles, and enhances overall skin quality. Patients often notice a natural “lifted” look over time.

Treatment course

Usually involves a series of 3 treatments spaced 6–8 weeks apart. Maintenance is recommended once a year.

Recovery

Minimal downtime. Swelling, redness, or tenderness may occur but usually resolves within a few days. Massage of the treated area is typically recommended to help the product integrate evenly.

Key advantage

Provides gradual, natural-looking improvement that lasts up to two years or more.

Hyperdilute Radiesse

Radiesse is traditionally used as a dermal filler, but when diluted with saline and anesthetic solution, it becomes a biostimulant that focuses on improving skin tone and elasticity rather than adding volume. This technique is called Hyperdilute Radiesse.

Treatment areas

Effective for the lower face, jawline, neck, décolletage, arms, abdomen, and above the knees.

Benefits

Tightens skin, reduces fine lines and crepiness, and thickens the dermis for a healthier appearance.

Treatment course

Typically requires 2–3 treatments performed every 8–12 weeks. Maintenance treatments are recommended every 12–18 months.

Recovery

Minimal downtime with mild swelling or bruising possible for a few days.

Key advantage

Targets areas beyond the face, offering full-body skin rejuvenation.

Smiling woman with smooth, radiant skin after Hyperdilute Radiesse treatment to improve tone and elasticity — Hyperdilute Radiesse enhances skin tone and elasticity by stimulating collagen without adding volume.

How Biostimulant Treatments Are Performed

Biostimulant injections are performed in the office setting at Laser & Cosmetic Surgery Specialists in Newburgh, NY. Treatments usually take about 30 minutes. A topical anesthetic is applied for 30 minutes beforehand to ensure patient comfort. The injections themselves are well tolerated and involve no incisions or surgical techniques.

Because these treatments rely on the body’s own collagen-building process, results appear gradually. Patients often notice subtle improvements after their first session, with optimal results developing over several months.

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Schedule a Consultation

If you are interested in learning more about biostimulant injectables in Newburgh, NY, schedule a consultation at Laser & Cosmetic Surgery Specialists. Dr. Rubinstein and his team can help you determine which treatment option—PDGF-BB, Sculptra, or Hyperdilute Radiesse—best meets your needs. Call the office today to start your journey toward healthier, more youthful-looking skin.

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Woman relaxing by window with a warm drink, representing minimal downtime after biostimulant skin treatments — Biostimulant treatments involve minimal downtime, allowing most patients to resume daily routines almost immediately.

Recovery and Aftercare

One of the benefits of biostimulant treatments is the minimal recovery required. Patients can usually return to daily activities immediately. The following guidelines may be recommended:

Avoid vigorous exercise for 24 hours.
Expect mild swelling, redness, or bruising that typically resolves in a few days.
Massage may be recommended after Sculptra or Hyperdilute Radiesse to promote even distribution.
Temporary lumpiness with PDGF-BB injections is rare but may last for several weeks as collagen develops.

Overall, downtime is minimal, and most patients resume normal routines right away.

Woman with flawless skin symbolizing safe and minimal-risk results from properly administered biostimulant injections

Risks and Considerations

Biostimulant injections are considered safe when performed by trained injectors. However, like all medical procedures, there are potential risks:

Small risk of nodules with Sculptra or Hyperdilute Radiesse. This risk is minimized with proper patient selection, skilled injection technique, and adherence to aftercare instructions.
Temporary redness, swelling, or bruising at injection sites.
With PDGF-BB, possible pinkness, swelling, or small bumps that typically resolve within 4 weeks.

It is also important to note that Hyperdilute Radiesse and PDGF-BB injections are considered off-label uses of these products. While not FDA-approved for these exact applications, they are commonly and safely performed in aesthetic medicine by experienced providers. During consultation, Dr. Rubinstein and his team will review each patient’s medical history and aesthetic goals to ensure treatment is appropriate and safe.

Why Choose Dr. Rubinstein in Newburgh, NY?

Patients throughout the Hudson Valley trust Dr. Rubinstein and Laser & Cosmetic Surgery Specialists for their injectable treatments because of the practice’s commitment to patient safety, natural results, and advanced regenerative techniques. Dr. Rubinstein is a double board-certified facial plastic surgeon who has dedicated his career to helping patients look and feel their best through individualized care. His team of skilled injectors is experienced in the latest biostimulant methods, ensuring each patient receives a treatment plan tailored to their needs. With a state-of-the-art office in Newburgh, NY, patients benefit from expert care in a comfortable and welcoming environment.

Frequently Asked Questions About Biostimulants

What are biostimulants used for?

Biostimulants are used to improve skin quality, reduce fine lines, and restore volume by stimulating the body’s natural collagen and elastin production. They can also enhance skin thickness and provide a youthful glow.

How long does it take to see results?

Results develop gradually as new collagen forms. Most patients notice improvements within three months, with continued enhancement over the next several months. Full results are often seen after completing the recommended series of treatments.

How many treatments will I need?

The number of treatments depends on the product and the area being treated. Sculptra often requires three sessions, Hyperdilute Radiesse typically requires two to three, and PDGF-BB may require one to three. Maintenance treatments help sustain results.

Is there any downtime after treatment?

Downtime is minimal. Most patients return to daily activities immediately, although exercise should be avoided for 24 hours. Temporary redness, swelling, or bruising may occur but usually resolves quickly.

Are biostimulant injections safe?

Yes. When performed by trained injectors, these treatments are considered very safe. Risks such as nodules or temporary swelling are rare and typically resolve on their own.

How do biostimulants differ from fillers?

Fillers add immediate volume to specific areas, while biostimulants stimulate collagen growth over time. This makes biostimulants ideal for patients seeking long-lasting improvements in skin quality rather than quick volumization.

Can biostimulants be combined with other treatments?

Yes. Many patients combine biostimulant injections with Botox, dermal fillers, or skin treatments such as lasers for more comprehensive rejuvenation. Dr. Rubinstein will design a personalized plan to achieve your best results.

Do results look natural?

Absolutely. Because biostimulants work by stimulating natural collagen production, the improvements are gradual and subtle, enhancing your appearance without an overdone look.

How long do results last?

With proper maintenance, results can last one to two years or longer depending on the product and individual factors. Annual or biannual touch-ups are often recommended.

Is PDGF-BB better than PRP?

PDGF-BB is significantly more potent than PRP and does not require a blood draw, making it more comfortable for patients. It is also more consistent in its effects, whereas PRP results may vary depending on the patient’s own blood composition.

What areas can Hyperdilute Radiesse treat?

This treatment is particularly effective for the lower face, jawline, neck, chest, arms, abdomen, and above the knees—areas where skin crepiness and laxity often appear.

Who is a good candidate for biostimulants?

Good candidates are patients seeking natural-looking skin rejuvenation without surgery. Those with mild to moderate skin laxity, fine lines, volume loss, or crepiness often benefit most. A consultation will determine if the treatment is right for you.

Last modified October 14, 2025 by Dr. Ran Y. Rubinstein.